User blog comment:Slasher Chaos/Playing Dead Rising 2/@comment-1918971-20101001155957/@comment-399926-20101001175527

As long as you have a survivor armed with the Merc Assault Rifle nearby, he's incredibly easy. I used Jasper for that after bringing him along for the Run for the Money case. He'll shoot to interrupt Antoine's healing and do a good deal of damage to him in the mean time. I imagine with multiple survivors, you could kill Antoine without even attacking him.