Chuck arrives at the Shoal Nightclub to meet Rebecca Chang to meet Rebecca's source, only to find the club empty. The door shuts and Crystal Bailey walks out with a katana. Crystal and her twin, Amber, is the source that submitted the false video the Channel 6 Action News. Amber throws Rebecca to the ground as the twins draw their swords, ready to eliminate him.
After the battle, one of the sisters is killed, in which the other cries that she was her other half. Furious, she promises that Chuck will never get out of Fortune City alive. She then takes a dagger and commits suicide. Chuck then unties Rebecca and both discuss what Rebecca overheard from the twins.
Focus only on one twin, be sure to take a fast weapon and land a few strikes before running/jumping away to dodge.
Only focus on one of the twins. Going after both only wastes time, weapons and health.
Attacking the twins usually interrupts their attacks.
Dodging may be a little tricky, since the twins run quite fast, but it can be done with a bit of practice.
When the both of them are together, run away or else one of them will certainly hit Chuck.
They usually run away after hitting Chuck two or three times, which gives Chuck time to heal.
It is easy to deal damage to the twins, but avoiding their damage is hard, so bring one good weapon and a few healing items.
Knife Gloves (Bowie Knife + Boxing Gloves) are also a really easy way to kill the twins. As long as Chuck only attacks either Amber or Crystal, it should kill them in 5–15 hits. If Chuck has more than 6 health bars, then he will not need to heal at all during the battle.
If one of the twins performs a sliding attack, let them begin their sword swing before attempting to dodge. The slide looks like a blind charge, but it homes in on Chuck.
The Super Slicer's alternate attack can be used to run laps around the nightclub while dealing damage. Caution is required as Rebecca can be injured while doing so.
Two shotguns can be found at the gun shop in Palisades Mall and one can be found behind the counter across from the nightclub. Use the shotgun (in the aiming view) and target one of the twins as they each charge Chuck. It should take around 25–30 shots to kill one of them.
Take the light machine gun in the cashier area from the previous case Case 3-2: Run for the Money. Alternatively, go into the middle of the Yucatan Casino and climb to the top of the Tiki Statue, where Chuck will find another LMG and a Zombrex. So with 2–3 pain killer drinks (below), and one LMG, travel to the nightclub. Before entering, be sure to grab the shotgun underneath the counter opposite from the nightclubs entrance. Immediately after the cut scene, drink one of the pain killers, then use the machine gun on either twin. Once the machine gun is out of ammo, switch to the shotgun, and drink another pain killer if needed. Chuck should be able to finish off whichever twin Chuck is focusing on with a few blasts from the shotgun.
Use a Freedom Bear (Robot Bear + LMG). Put the Freedom Bear in one of the corners and make the Twins follow Chuck into its line of fire. Chuck can then defeat them off with the shotgun.
Before Chuck enters the nightclub, at the bar create the Pain Killer drink (Beer + Beer). This allows Chuck to half damage for one minute. Make 2 or 3 of these.