After a grenade has been thrown, it can be picked back up and thrown again; however, it cannot be placed in Chuck's inventory after it has been thrown.[Verification needed]
A grenade can be armed by shooting it with any firearm, where it will explode after 5 seconds.[Verification needed]
After the grenade is armed, it will start to smoke before it explodes.
There are two grenades near the "island" of fenced grass near the 4x4 beside the Fortune City Hotel.
Between the iron bar gates and the Fortune City Hotel along the wall on the grass. Starting from the entrance to the Fortune City Hotel, climb onto the grass and go southeast while walking as close as possible to the wall. Just before Chuck comes upon the iron bar gates, there are two grenades.